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Application, Advantages, and Disadvantages of Rapid Mixer Granulator

Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator is a significant drug gear utilized during the time spent quick wet blending, homogenization, humidification, and powder grinding. Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator assumes a significant function in the granulation line of strong measurement structures. Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator interfaces with downstream gear liquid bed dryer structure shut granulation. Be that as it may, notwithstanding the various significance of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator, many individuals are very new to this hardware.

There are various applications of Rapid Mixer Granulator. Like most drug types of gear, this machine assumes a significant function in this industry. Its principal intention is blending, pulverizing, humidifying, homogenizing, and serving drug materials. Besides, you can utilize this gear to blend both dry and wet powders. It can blend powders in a wide scope of working conditions, for example, working without shifting weight zones. A high shear granulation is an ideal decision for exceptionally strong material. Ordinarily, a low shear blender granulator machine can’t deal with such materials since they have a high measure of the hydrophilic polymer. Rapid Mixer Granulators (RMG) are utilized for tablet fabricating measure which requires homogenous blending, controlled granule size and simultaneously guaranteeing extraordinary decrease in preparing time. In pharmaceutical processing, rapid mixer granulators are commonly used devices. It is used before compression to blend the medicinal ingredients to render the granules and is often called a high-shear mixer. In the rapid mixer granulator, the impellers and the chopper are primarily responsible for wet granulation.

Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator has a few favorable circumstances of blending gear in with low shear. There are several reasons why most pharmaceutical manufacturing companies are renowned for this unit. A portion of the advantages incorporates granulation of exceptionally durable materials that contain hydrophilic polymers. Such granulation can’t be gotten from low shear. In high shear granulation, the whole granulation measure requires more limited time contrasted with low shear. Just a small bunch of folio is required which assists with keeping the expense of creation at a negligible level. There is a lesser presentation of laborers to clean with high shear granulation, because of decreased residue age in high shear granulation measure. You can foresee the result of the granulation measure when you utilize a high shear blender. It is anything but difficult to accomplish a uniform molecule size dissemination with high shear, and reproducible less friable granules. You can accomplish drying in more limited time with Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator

A high shear blender has drawbacks or disadvantages too. It might cause the debasement of powder, particularly for delicate or thermolabile powders. Over-wetting may cause the creation of huge protuberances. It creates less compressible granules. It possesses a tight scope of activity conditions. Fundamentally, this clarifies all the imperative parts of a high shear blender.

Hence, you can see that a sealed jar with a variety of mixing machinery that processes the powder is an elevated shear mixer granulator, either from below, above, or sideways. A circular and compact granule is the result/output of this operation.

 

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